Download PDF. 1 / 3 Pages. Previous article. Go back to website. Next article. HARRIS D., Paul BRINCK M., Patricio. Un análisis retrospectivo de cavernomatosis de la vena porta en Chile: II. Hemorragia, tratamiento y pronóstico. Rev. chil. HARRIS D., Paul BRINCK M., Patricio. Un análisis retrospectivo de cavernomatosis de la vena porta en Chile.: I. Perfil clínico y de laboratorio. Rev. chil. pediatr.

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However, in the general population, its role in PVT development seems less clear, as it is considered a weak prothrombotic risk factor. Systemic risk factors, like MPD or other prothrombotic disorders, seem not to affect short-term survival[ 99 ].

Splanchnic vein thrombosis in candidates for liver transplantation: Preserved liver function with precipitating factors splenectomy, surgical portosystemic shunting, TIPS dysfunction, thrombophilia. Diagnosis of portal venous invasion by pancreatobiliary carcinoma: Three-dimensional gadolinium-enhanced MR angiography of vascular complications after liver transplantation. Thrombolytic therapy in patients with portal vein thrombosis: It has been demonstrated in rats, that the progressive obliteration of the portal vein stimulates apoptosis of hepatocytes in the hypoperfused lobe[ 10 ], while increasing the mitotic activity in the normal perfused one.

Percutaneous transhepatic treatment of symptomatic mesenteric venous thrombosis. Webb LJ, Sherlock S.

Malformación cavernomatosa de la vena porta

Eversion thromboendovenectomy in organized portal vein thrombosis during liver transplantation. A population-based autopsy study. PVT can be classified into four categories, depending on the extension: In fact, when thrombosis is extended to both portal and mesenteric veins, the risk of bowel ischemia is considerable and mortality high, despite a lower risk of variceal bleeding[ 61 ]. Changing perspectives in portal vein thrombosis and liver transplantation.


The ubiquitous and long-term use of anticoagulants in cirrhotic patients with PVT should not be considered correct practice, until their safety and efficacy has been completely tested[ 62 ]. Usually, the original portal vein becomes a thin, fibrotic cord, which is difficult to visualize[ porya9 ].

Current state of portosystemic shunt surgery. This article has been cited by other articles in PMC.

Portal vein thrombosis: Insight into physiopathology, diagnosis, and treatment

If CT scan is not rapidly available, obtain Doppler-sonography. Surgical restoration of portal flow corrects procoagulant and anticoagulant deficiencies associated with extrahepatic portal vein thrombosis. Single center experience of 39 patients with preoperative portal vein thrombosis among adult living donor liver transplantations. Local or systemic pro-thrombotic factors, alone or together, can play an important role in PVT pathogenesis, which is complex and different in each clinical context and in each patient.

Chronic PVT On the other hand, chronic PVT can be nearly asymptomatic, except for the presence of varices, cutaneous collaterals, or ascites[ 62 ].

J Cancer Res Clin Oncol. Dose and duration of anticoagulants If thrombosis is recent and there is no underlying thrombophilic condition, anticoagulation should be administered for mo, as a complete portal vein recanalization can occasionally be delayed[ 79,- ]. Comparative analysis of the results of orthotopic liver transplantation in patients with and without portal vein thrombosis. It appears to be more accurate than US or computed tomography CT scans in discovering portal invasion by tumors[ 7778 ].

Cholestasis as presenting symptom of portal cavernoma.

Lai L, Brugge WR. Etiology of portal vein thrombosis in adults. At this caernoma, the development of a hyperkinetic circulation, characterized by low systemic vascular resistance and a high cardiac output, is common[ 3 ].


Finally, shunt surgery distal splenorenal shunt or Rex shunt, in children might be applied as the last choice, and only in absence of splenic or superior mesenteric vein thrombosis[ ]. Typically, patients with an advanced thrombosis do not always remember any previous trigger event or disease[ 2263cavernoa ].

Am J Med Sci.

Although spontaneous resolution of PVT has been reported in the literature[], a specific therapeutic management is mandatory to resolve portal vein obstruction and avoid serious complications.

Inherited coagulation disorders cavernma cirrhotic patients with portal vein thrombosis. However, this process results in a progressive loss of tissue and might be responsible for the impairment of hepatic synthetic function observed in advanced stages of portal vein cavenoma 11 ]. The first successful liver transplant in a patient with a thrombosed portal vein was reported by Shaw et al[ ], in Anticoagulation in acute PVT Although PVT might be compared to other cases of deep vein thrombosis, there is no randomized controlled trial regarding the use of anticoagulants in acute PVT[ ].

Recent portal or fe venous thrombosis: Incidentally, a pragmatic approach, such as endoscopical eradication of varices prior to commencement of anticoagulation, should be reasonable[ vens ]. Acute liver failure, bleeding from esophageal varices, and massive ascites could rapidly occur and immediate retransplantation must be quickly attempted in case of severe worsening of liver function[ ].