Chondroblastic osteosarcoma as defined by WHO is a histological entity characterized by predominant presence of chondroid matrix, which tends to exhibit a. Giant Chondroblastic Osteosarcoma Mandible-A Rare Case Report. Shubhangi Kedar, Smita Nagle, Saurabh Agarwal, Sunita Bage, Amey Kothekar, Rohini. MalaCards based summary: Chondroblastic Osteosarcoma, also known as chondrosarcomatous osteogenic sarcoma, is related to chondrosarcoma and.

Author: Mezilar Yomuro
Country: Nepal
Language: English (Spanish)
Genre: Career
Published (Last): 13 April 2014
Pages: 242
PDF File Size: 4.47 Mb
ePub File Size: 15.31 Mb
ISBN: 367-8-47945-379-4
Downloads: 80904
Price: Free* [*Free Regsitration Required]
Uploader: Goltile

Time passes, do what you need, stay strong and see the end of the pain in sight. The osteosaecoma or classical osteosarcoma is the variant that occurs most frequently.

At other areas, the borders were relatively well defined with a narrow zone of transition and surrounded predominantly by a thin radiolucent halo separating the lesion from normal bone as an encapsulation.

I hate this cancer; I cry to see her and all these children chondroblasitc through this treatment, to see them so sick, to see these other families watch their precious children have to endure this disease, as we have watched Taylor.

Later, after several months of chemo, Logan was faced with the dreadful decision of whether to have the hemipelvic amputation or not. The limiting factor is time to incorporation. There are three basic questions to be answered during staging:. The requisite tissue can be obtained via needle biopsy or through open methods.

Once pathological evaluation has been performed and a histologic grade assigned, all of the information is assimilated to determine the “personality” of the tumor. Special consideration must be given to skeletally immature patients, as continued growth of the uninvolved extremity may pose additional problems and require multiple future operations. The two most common sites of spread of osteosarcoma are lung and bone. Incisional biopsy was performed from the cohndroblastic aspect of swelling.

With infiltrative medullary growth. The lobulated appearance of the mass could be appreciated. This is the basis for utilization of systemic chemotherapy. Fine-needle aspiration FNA of osseous ostsosarcoma is routinely performed in major medical centers. OS of maxillofacial region have variable appearances clinically as well as radiologically which poses a diagnostic challenge for clinicians especially in its imaging diagnosis.


In the present case, the lesion was diagnosed and surgical treatment was provided with hemimandibulectomy along with chemotherapy. Clinico-histologic parameters of osteosarcoma patients with late relapse.

Giant Chondroblastic Osteosarcoma Mandible-A Rare Case Report

Therefore, care of individuals with osteosarcoma is usually best undertaken in a multidisciplinary cancer center where the resources and personnel requisite to the care of these complex patients are most readily available. Past history revealed a tooth extraction of the left lower premolar tooth after the occurrence of dental carries, occasionally associated with oral bleeding.

A posting often results in an “online discussion” of the topic. However, the present case showed radiographic evidence of type 1C pattern which exhibits a less sharp limit. Guidelines Upcoming Special Issues. A tribute to Logan The classical osteosarcoma is the most frequent variant, which develops in the medullary region of the bone and can be subdivided in osteoblastic, chondroblastic and fibroblastic histological types, depending upon the extracellular matrix produced by tumor cells [ 6 ].

Tooth mobility may be related to osteosarcoma of the mandible and maxilla and in some situations, may be the first sign of the disease. The present case falls into the group of osteogenic type without bone destruction. How to cite this article: I wish I had known that I would get so hopeful that I would feel that I could have a child and might even live to see her 20th birthday.

After treatment, Cari had a little boy In OctoberI married the man of my dreams. Silveira Martins,CEP: Osteosarcoma of the jaw: While differences between amputation and limb-sparing procedures do exist, long term outcomes with regards to patient function and satisfaction appear to be similar DiCaprioRefaatNagarajan The days since have been hard for our family, but they have also been amazing.

Complete surgical excision with negative margins continues to be the mainstay of treatment but osteosarcomas of maxillofacial region pose difficulties in obtaining tumor-free margins because of their complex anatomy and close proximity to the cranium [ 20 ]. Osteosarcoma is the name given to a heterogeneous group of chohdroblastic spindle cell tumors that have as their common feature the production of immature bone, also known as osteoid.


Read our Comprehensive Guide for the Newly Diagnosed. On January 22ndmy son had a through-knee amputation. Floor of the nasal cavity was breached and irregular on the left side. Functional outcomes after amputation vary and are dependent on many factors.

Now that I have been through chemo, I feel more positive. Surgery requires much preoperative planning and evaluation.

I love this sweet little girl with all my being; she is my baby. The syndromes and beyond. In this type, tumor consists of atypical chondroid areas composed of pleomorphic and atypical binucleate cells, having large hyperchromatic nuclei and prominent nucleoli. The quantity of osteoid described is varied. A year old man, reported to the Department of Oral Medicine and Radiology, Manav Rachna Dental College, Faridabad, Haryana, India complaining of a swelling in the left anterior region of upper jaw since 1 year.

Giant Chondroblastic Osteosarcoma Mandible-A Rare Case Report | OMICS International

Is there a difference in the prognosis of patients with primary osteosarcoma with poor response to neoadjuvant chemotherapy between grades I and II of Huvos?

The results of the biopsy and imaging studies provide physicians with an idea of the “personality,” or stage, of the disease. During anamnesis, the osteosarcoa mentioned an increase in volume in the premaxillary region, with 5 months of chomdroblastic, which developed with painful symptomatology and mobility of the maxillary anterior teeth.

If any question exists, a biopsy should be performed.

chondroblastic osteosarcoma

Info – Admin Resources in pathology Technical section. The product of this gene is a protein that acts to suppress growth of cells with damaged DNA tumor suppressor. I am Blessed and grateful for this sweet life God has entrusted to me my sweet girl, Taylor.

Post-surgical obturator was then placed.