ERYTHROMYCIN LACTOBIONATE PACKAGE INSERT PDF
Erythromycin Lactobionate 1g Powder for Solution for Infusion – Summary of Product Characteristics (SmPC) by ADVANZ Pharma. Erythromycin Lactobionate I.V. is a sterile presentation of erythromycin. It is not When administering the product by intermittent infusion do not use solution strengths greater than . includes any possible side effects not listed in this leaflet. Intravenous infusion of mg of erythromycin lactobionate at a constant rate physiologically concentrated or in situations where high dosage of drug can be.
|Published (Last):||15 January 2004|
|PDF File Size:||2.17 Mb|
|ePub File Size:||10.47 Mb|
|Price:||Free* [*Free Regsitration Required]|
Erythromycin Lactobionate – I.V. Information –
Infants born to women treated during pregnancy with oral erythromycin for early syphilis should be treated with an appropriate penicillin regimen.
We comply with the HONcode standard for trustworthy health information – verify here. Hypotension, bradyarrhythmias and lactic acidosis have been observed in patients receiving concurrent verapamil, a calcium channel blocker. Parents should be informed to contact their physician if vomiting or irritability with feeding occurs. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:.
GranulesErycDate of revision of the text. Bronchitis ciprofloxacinamoxicillindoxycyclineazithromycinAugmentinMore There have been published reports suggesting when oral erythromycin is given concurrently with theophylline there is a significant decrease in erythromycin serum concentrations.
Erythromycin Lactobionate – I.V.
However, many people have no side effects or only have minor side effects. Erythromycin is excreted principally by the liver, so caution should imsert exercised in administering the antibiotic to patients with impaired hepatic function or concomitantly receiving potentially hepatotoxic agents.
Available for Android and iOS devices. Erythromycin inssert its antimicrobial action by binding to the 50S ribosomal sub-unit of susceptible microorganisms and suppresses protein synthesis. The same applies for streptomycin, tetracyclines and colistin. Bolus oackage is not recommended. This may result in QTc prolongation and cardiac arrhythmias including ventricular tachycardia, ventricular fibrillation and torsades de inseet.
If you have questions about side effects, call your doctor. Intravenous erythromycin should be replaced by oral erythromycin as soon as possible. Post-marketing reports indicate that co-administration of erythromycin with ergotamine or dihydroergotamine has been associated with acute ergot toxicity characterised by vasospasm and ischaemia of the central nervous system, extremities and other tissues see section 4.
There have been reports suggesting erythromycin does not reach the foetus in adequate concentrations to prevent congenital syphilis.
Pseudomembranous colitis has been reported rarely in association with erythromycin therapy see section 4. Active ingredient erythromycin lactobionate.
This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.
Erythromycin Lactobionate 1g Powder for Solution for Infusion
lactobioonate There are no pre-clinical data of relevance to the prescriber which are additional to that already included in other sections of the SPC. The following have been reported: Erythromycin can be excreted into breast-milk.
Erythromycin Lactobionate 1g Powder for Solution for Infusion. Newborn infant birth to 1 month: There have been reports that erythromycin may aggravate the weakness of patients with myasthenia gravis.
Alternative Step 2 diluents: Erythromycin is usually active against most strains of the following organisms both in vitro and in clinical infections:. Be ready to tell or show what was taken, how much, and when it happened. Erythromycin antagonises the action of clindamycin, lincomycin and chloramphenicol.
Particular care should be taken with medications known to prolong the QTc interval of the electrocardiogram. Patients receiving erythromycin concurrently with drugs which can cause prolongation of the QT interval should be carefully monitored. You may also report side effects at http: Marketing authorisation holder 8. There have been reports that maternal macrolide antibiotics exposure within 7 weeks of delivery may be associated with a higher risk of infantile hypertrophic pyloric stenosis IHPS.
Erythrocin Lactobionate Rating No reviews – Add your review.
Find out more here. Ear and labyrinth disorders: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Marketing authorisation number s 9. Read all information given to you.
There have been reports of infantile hypertrophic pyloric stenosis IHPS occurring in infants following erythromycin therapy. Prolonged QTc interval and ventricular arrhythmias have been reported rarely packahe patients receiving intravenous erythromycin. Solutions containing glucose may also be used but sodium bicarbonate must first be added as a buffer to ensure neutrality.
Dental Abscess amoxicillinmetronidazoleFlagylerythromycinclarithromycinAmoxilMore Erythromycin is contraindicated in patients taking simvastatin, tolterodine, mizolastine, amisulpride, astemizole, terfenadine, domperidone, cisapride or pimozide.
The concomitant use of erythromycin with some of these drugs is contraindicated See sections 4. Rare reports of rhabdomyolysis have been reported in patients taking these drugs concomitantly. Drugs that induce CYP3A4 such as rifampicin, phenytoin, carbamazepine, phenobarbital, St John’s Wort may induce the metabolism of erythromgcin. Reporting of suspected adverse reactions Reporting suspected adverse reactions after authorisation of the medicinal product is important.
Allergic reactions ranging from urticaria and mild skin eruptions to anaphylaxis have occurred.