INFED PACKAGE INSERT PDF

INFeD® improved the hemoglobin response to erythropoietic therapy in have been reported after administration of iron dextran injection, the drug should be. iron dextran – Drug Summary. Jump to INFeD Intramuscular Inj Sol: 1mL, 50mg . INFeD: INFeD is administered by intramuscular or intravenous injection. Allergan, Inc.: Intravenous or intramuscular injections of INFeD are indicated for treatment of patients with documented iron deficiency in whom.

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A test dose of 25 mg infused over 5 inred should be given. Concurrent use of deferiprone with iron supplements has not been studied. Your Name Your name is required.

Iron dextran (INFeD)

Observe patient for at least 1 hour after test dose administration. The table and formula described under I. The contribution of iron to infectious processes is unclear, but iron dextran should not be administered during the acute phase of infectious renal disease manufacturer’s information.

If necessary, iron may be given in short courses, but since iron and trientine each inhibit oral absorption of the other, 2 hours should elapse between administration of trientine and iron doses. Alternatively the total dose imfed be calculated: However, iron deficiency may develop, especially in children and menstruating or pregnant women, or as a result of the low copper diet recommended for Wilson’s disease.

The use of iron dextran to prevent iron deficiency in patients requiring long-term parenteral nutrition support is controversial; some experts advocate the use of iron to treat a deficiency if it occurs vs. Subcutaneous injection of iron dextran results in slow absorption and staining inswrt subcutaneous tissue. Dilute the total calculated dose see Dosage packag to mL of 0.

Too much iron can be toxic, and iron is not easily eliminated from the body. It should be remembered that iron deficiency anemia will not appear until essentially pwckage iron stores have been depleted. Am J Kid Dis.

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Dilution Iron Dextran (imferon ®) – GlobalRPH

Total dosage with iron dextran must be individualized according to the patients age, weight, and the degree of the iron-deficiency anemia. Once taken into reticuloendothelial cells, the iron from the iron dextran complex is separated and added to the body’s total iron stores. Ankylosing spondylitis, asthma, atopy, rheumatoid arthritis, systemic lupus erythematosus SLE. Consult specialized references for amount of test dose to be given.

Iron dextran is contraindicated for use in patients with anemia not associated with iron deficiency. Before administering therapeutic doses by any route, a test dose of of iron dextran should be given by the route and method of administration for which therapeutic doses are to be administered. These dimercaprol-iron complexes are more toxic than the metal alone, especially to the kidneys. Iron dextran should only be used in patients with a clear and confirmed need for parenteral iron therapy.

Specific guidelines for dosage adjustments in hepatic impairment are not available. Fatal anaphylactoid reactions have occurred during the parenteral administration of iron dextran. The extent of risk for anaphylactoid inffd to any specific iron dextran product is unknown and may vary among products. Adult and Adolescent menstruating, premenopausal women. There is some concern that intravenously administered iron is not used appropriately by the body.

Safety and efficacy have not been established. DO NOT mix iron dextran with other medications. Normal hemoglobin males and females over 15 kg 33 lbs. If test dose uneventful, give the remainder of the total dose as 25 mg of iron dextran per day IM or slow IV until the total calculated dose see equation is given. Minor Iron stores should be replete before and during treatment with an ESA.

Distribution of iron dextran following intramuscular or intravenous injection involves uptake by reticuloendothelial cells of the liver, spleen, and bone marrow. However, trace amounts of unmetabolized iron dextran are excreted in breast milk. Both animal and human data indicate that the bulk of intravenous iron is sequestered in the reticuloendothelial system i.

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Methoxy polyethylene glycol-epoetin beta: Serious anaphylactoid reactions require appropriate resuscitative measures. Infants and Children 4 months and older weighing 5 to 9.

Patients with hepatic disease should receive iron dextran with caution. Before administering therapeutic doses, a test dose of 25 mg 0. If no adverse reactions are observed, INFeD can be given according to the following schedule until the calculated total amount required has been reached.

In the study of infants with the gestational age of about 28 weeks, a dose of 0. If test dose uneventful, infuse the remainder of the total calculated dose see equation IV over 2 to 6 hours. In normal, healthy adults, some daily loss of iron occurs through normal skin, hair, and nail loss, and GI losses.

Adults, Adolescents, and Children weighing 10 kg or more. Therapy, thus, should aim at not only replenishment of hemoglobin iron but iron stores as well. A test dose should be given prior to administration of the initial therapeutic dose.

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General Unwarranted therapy with parenteral iron will cause excess storage of iron with the consequent possibility of exogenous hemosiderosis. Patients receiving exogenous iron therapy require periodic monitoring of hematologic and hematinic parameters i.

Subcutaneous injection results in slow absorption and staining of subcutaneous tissue. Instructions for test dose administration for all indications. Anaphylaxis and other hypersensitivity reactions have been reported after uneventful test doses as well as therapeutic doses of iron dextran injection. Oral iron supplementation should be discontinued before parenteral administration of iron. According to the manufacturer, caution should be infsd if iron dextran is administered to a nursing mother.